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1.
Infect Disord Drug Targets ; 21(8): e211221191975, 2021.
Article in English | MEDLINE | ID: covidwho-1115357

ABSTRACT

INTRODUCTION: COVID-19 has caused a great deal of fear in different communities. In this study, we reported the recovery of a diabetic elderly woman with a history of asthma from COVID-19 infection. CASE PRESENTATION: A 61-year-old woman was hospitalized due to dyspnea and low blood O2 saturation and was later diagnosed with COVID-19, as confirmed by PCR. The patient had a history of asthma and diabetes and used salbutamol and Atrovent spray. She also had a history of hospitalization at one month prior to the current admission. Despite all these, COVID-19 was successfully managed, and she was discharged with a good clinical condition after the improvement of respiratory complications. CONCLUSION: Despite having an advanced age and underlying diseases (diabetes and asthma), the recovery of this elderly woman shows that even such patientscandefeatCOVID-19 as long as the disease is not progressed to advanced phases and appropriate therapeutic measures are taken. By reporting such cases, it is possible to give people hope and motivation and reduce their fear of the disease.


Subject(s)
Asthma , COVID-19 , Diabetes Mellitus , Aged , Asthma/complications , Asthma/drug therapy , Female , Hospitalization , Humans , Middle Aged , SARS-CoV-2
2.
Future Cardiol ; 17(1): 113-118, 2021 01.
Article in English | MEDLINE | ID: covidwho-632332

ABSTRACT

The mortality rate of coronavirus disease-19 (COVID-19) has been reported as 1-6% in most studies. The cause of most deaths has been acute pneumonia. Nevertheless, it has been noted that cardiovascular failure can also lead to death. Three COVID-19 patients were diagnosed based on reverse transcriptase-polymerase chain reaction of a nasopharyngeal swab test and radiological examinations in our hospital. The patients received medications at the discretion of the treating physician. In this case series, chest computed tomography scans and electrocardiograms, along with other diagnostic tests were used to evaluate these individuals. Sudden cardiac death in COVID-19 patients is not common, but it is a major concern. So, it is recommended to monitor cardiac condition in selected patients with COVID-19.


Subject(s)
COVID-19/complications , Death, Sudden, Cardiac/etiology , SARS-CoV-2 , Tomography, X-Ray Computed/methods , Aged , COVID-19/diagnosis , COVID-19/epidemiology , Female , Humans , Male , Middle Aged
3.
Virology ; 548: 1-5, 2020 09.
Article in English | MEDLINE | ID: covidwho-361254

ABSTRACT

INTRODUCTION: During the recent months, COVID-19 has turned to a global crisis claiming high mortality and morbidity among populations. Despite the high prevalence of the disease, it has currently no definitive treatment. We here reported the effects of intravenous immunoglobulin (IVIG) administration in severely ill COVID-19 patients diagnosed based on PCR and radiology tests. CASE PRESENTATION: Five severely ill COVID-19 patients in whom standard treatments failed were administrated with IVIG which prevented the deterioration of clinical symptoms. All the patients were treated with high-dose IVIG (0.3-0.5 g/kg) for 5 consecutive days so that no patient would receive lower than 25 g of the drug. All the patients showed a desirable therapeutic response and were discharged from the hospital with a stable clinical condition after being recovered. CONCLUSION: Treatment with IVIG at the therapeutic dose of 0.3-0.5 g/kg can improve the clinical condition and O2 saturation and prevent the progression of pulmonary lesions in COVID-19 patients with severe symptoms in whom standard treatments have failed.


Subject(s)
Betacoronavirus , Coronavirus Infections/therapy , Immunoglobulins, Intravenous/therapeutic use , Pneumonia, Viral/therapy , Aged , COVID-19 , Coronavirus Infections/drug therapy , Disease Progression , Female , Humans , Immunoglobulins, Intravenous/administration & dosage , Male , Middle Aged , Pandemics , Pneumonia, Viral/drug therapy , SARS-CoV-2 , Treatment Outcome , COVID-19 Drug Treatment
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